Back in the halcyon days of 1986, before “toxic masculinity” had been formally identified as a virulent social disease and a talking point for cable news pundits, the then-rising playwright and performer Eric Bogosian unleashed “Drinking in America,” a one-act piece in which he played more than a dozen men — each captured under the influence of an intoxicant or two. Or several.

Alcohol figures prominently in the play, now being revived off-Broadway, with cocaine, heroin, and Quaaludes in key supporting roles. Yet Mr. Bogosian’s characters, who are as diverse in their lifestyle choices as they are in socio-economic status, are just as likely to be drunk on ambition, desperation, or even boredom. There’s the traveling salesman, pathetic in his attempts to impress an escort presumably half his age at most; or the film agent snorting and guzzling various substances as he alternately throws fits and shuts down pitches.